Durham, where history’s grit mingles with vibrant modernity, is a city that defies expectations. Imagine wandering through old tobacco warehouses repurposed as trendy eateries by day, then enjoying a craft beer in a buzzing pub by night. This isn’t just a place; it’s a testament to transformation, where tradition and innovation coexist seamlessly. From the intellectual hum of Duke University to the soulful rhythms of the local music scene, Durham pulses with an inviting, unpretentious energy. It calls you to uncover its layers, whether exploring the artsy downtown or unwinding in its serene parks. Here are the best areas to stay in Durham for first-time visitors, and I personally think they’ll make your trip unforgettable.

Quick Picks in Durham for First-time Visitors

The most romantic: The Lodge at Duke Medical Center, Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park
The most kids-friendly: Residence Inn by Marriott Durham Duke University Medical Center Area
The most stylish: Unscripted Durham
The best value: Durham Marriott City Center

Best Neighborhoods to Stay in Durham for First-Time Visitors

1. Downtown Durham
   • Highlights: Central location, historic sites, trendy restaurants, and bars.
   • Why Stay Here: Downtown Durham is perfect for first-time visitors due to its proximity to major attractions like the Durham Performing Arts Center (DPAC), American Tobacco Campus, and the Durham Bulls Athletic Park. The area is walkable and offers a lively nightlife.
     
2. Ninth Street/West End
   • Highlights: Eclectic shops, cozy cafes, and vibrant nightlife.
   • Why Stay Here: Known for its bohemian vibe, Ninth Street offers a variety of boutique shops, dining options, and a charming neighborhood feel. It’s close to Duke University and provides easy access to both the campus and the medical center.
     
3. Research Triangle Park (RTP)
   • Highlights: Innovative Business Hub, Educational Excellence, Green Spaces and Connectivity.
   • Why Stay Here: Stay in Research Triangle Park for its vibrant innovation ecosystem and proximity to leading universities, offering both professional opportunities and a balanced lifestyle with convenient amenities and green spaces.
     
4. Southpoint
   • Highlights: Upscale shopping, dining, and entertainment.
   • Why Stay Here: For those who prefer a more suburban feel with access to high-end shopping and dining, the Southpoint area is ideal. The Streets at Southpoint is a premier shopping destination, and there are numerous hotels in this area offering easy access to both Durham and nearby Chapel Hill.
     
5. Brier Creek
   • Highlights: Strategically located near Raleigh-Durham International Airport. Vibrant shopping and dining scene at Brier Creek Commons. Nearby attractions include Umstead State Park and Research Triangle Park.
   • Why Stay Here: Easy airport access, diverse accommodations, and proximity to shopping, dining, and attractions for a convenient stay.

Areas to Avoid:

1. East Durham
   • Why Avoid: While East Durham has been undergoing revitalization, some parts still face issues with crime and safety. It’s advisable to avoid this area, especially for first-time visitors who may not be familiar with the city.
2. Few Gardens
   • Why Avoid: Few Gardens has historically been known for higher crime rates and lower economic conditions. It’s best to steer clear of this area to ensure a safe and pleasant visit.

The Best Hotels in Downtown Durham

Downtown Durham, a blend of grit and gourmet, where old tobacco factories now house the best areas to stay in Durham. Imagine trendy eateries serving up local flavors amidst revitalized brick facades. It’s a neighborhood that tempts you to taste its past while indulging in its vibrant present.

Durham Marriott City Center

Enjoy a memorable stay at the Durham Marriott City Center, where exceptional service meets comfort. Revel in the welcoming atmosphere created by the attentive staff, including James, Kevin, Dominique, Noah, Alexandra, Betty, Raymond, and hotel manager Alex. The clean, well-appointed rooms offer stunning views of downtown Durham. Delight in the culinary expertise of Stuart at the hotel’s restaurant, Table South, who ensures an unforgettable dining experience. Perfect for both business and leisure, this hotel promises a warm, friendly ambiance.

Aloft Durham Downtown

Experience modern comfort at Aloft Durham Downtown, featuring recently renovated, spacious, and clean rooms. The hotel’s prime location places you just 75 meters from the Durham Performing Arts Center (DPAC) and within walking distance of numerous dining options. Guests rave about the friendly, attentive staff, particularly Eli at the front desk, who exemplifies exceptional service. Enjoy the convenient bar and snack/breakfast area in the lobby, and appreciate the warm hospitality of the chef. Perfect for business or leisure, Aloft Durham Downtown promises an unforgettable stay.

SpringHill Suites Durham City View

Stay at the exceptional SpringHill Suites By Marriott Durham City View, where beautiful property meets outstanding service. Enjoy spacious, clean rooms and a delicious breakfast each morning. The staff, including the night auditor Tyrus, morning associate Brittany, and front desk greeter Areia, provide warm and attentive service. Guests appreciate the convenient location, within walking distance to downtown Durham, DPAC, and the ballpark. Ideal for both leisure and business, the hotel offers unique fitness and pool facilities. Perfect for events, Jessica Dowell ensures seamless wedding block bookings.

Residence Inn by Marriott Durham Duke University Medical Center Area

Enjoy a comfortable and convenient stay at the Residence Inn by Marriott Durham Duke University Medical Center Area. Ideal for families and groups, the spacious, handicapped-accessible suites feature well-stocked kitchens and modern amenities. Guests appreciate the friendly and attentive staff, especially Bria, who ensures a seamless experience for room blocks and reunions. The hotel’s prime location offers easy access to Duke University, local attractions, and dining spots. Start your day with a well-stocked breakfast and enjoy the clean, beautifully updated rooms. Perfect for both short and extended stays.

Unscripted Durham, Part of JDV by Hyatt

Stay at Unscripted Durham, a revitalized, character-filled hotel blending comfort and style. Enjoy spacious, modern rooms with comfortable beds and artsy décor. The standout feature is the vibrant 4th-floor pool deck, perfect for unwinding after a busy day. Located in the heart of Durham, the hotel is close to all the action. Exceptional staff provide top-notch service, ensuring a memorable stay. Enjoy a complimentary glass of champagne on arrival, adding a touch of elegance to your experience.

The Best Hotels in Ninth Street/West End

Ninth Street/West End in Durham, where bohemian vibes meet culinary prowess, hosts some of the best places to stay in the city. Picture eclectic cafes and art galleries lining tree-lined streets. It’s a neighborhood that beckons with its indie spirit and diverse flavors, perfect for discovering Durham’s offbeat charm.

Hilton Garden Inn Durham-University Medical Center

Experience exceptional hospitality at the Hilton Garden Inn Durham-University Medical Center. From the moment you arrive, enjoy top-notch service from a dedicated staff, including Marquita, who ensures a perfect stay. The well-appointed, clean, and quiet rooms offer comfortable beds and modern showers. Start your day with a hot, fresh-to-order breakfast served by the dynamic team of Natalie and Alicia, whose upbeat service brightens every morning. Benefit from free parking, a well-maintained fitness center, and a convenient location within walking distance to shopping. Enjoy every aspect of your stay at this well-maintained hotel.

Kasa University Medical Center Durham

Experience a comfortable and convenient stay at Kasa University Medical Center Durham. The spacious, clean rooms come equipped with a fully stocked kitchen and a washing machine, ideal for long stays. The responsive virtual front desk ensures quick resolutions to any issues, providing peace of mind. Enjoy excellent building security and appreciate the reasonable pricing for such a well-maintained property. Note the proximity to train tracks, which can cause occasional noise. Overall, Kasa offers a superior, hotel-like experience with the comforts of home.

University Inn Duke

University Inn Duke offers a clean, modern, and comfortable stay with essential amenities. Spacious rooms feature wood flooring, a fridge with a sizable freezer compartment, and a microwave. Enjoy always-available hot coffee in the lobby and appreciate the quiet heating/AC units. The friendly staff, especially Cherriece at the front desk, provide exceptional service, making guests feel welcome. Though parking can be challenging, the hotel’s proximity to Duke Hospital and its patient discount make it an ideal choice for short stays.

The Lodge at Duke Medical Center

Enjoy a welcoming stay at The Lodge at Duke Medical Center, where the exceptionally friendly staff ensures a memorable experience. Modern, clean rooms and spacious common areas provide comfort and relaxation. Benefit from the convenient free shuttle service to Duke Hospital, or enjoy the short walking distance. Guests appreciate the thoughtful amenities, like fresh baked cookies and coffee in the afternoon. The staff, including manager Jenelle and shuttle driver Harry, go above and beyond to assist guests, creating a warm, hospitable atmosphere. Ideal for hospital visits or campus activities, with excellent parking and accessible rooms.

The Best Hotels in Research Triangle Park (RTP)

Research Triangle Park, where innovation thrives amidst serene landscapes, is a haven for the best areas to stay in Durham. Imagine sleek tech campuses nestled in lush greenery, buzzing with ideas and discoveries. It’s a hub that blends science with southern hospitality, inviting you to explore Durham’s dynamic intersection of intellect and nature.

Marriott Raleigh Durham Research Triangle Park

Experience exceptional hospitality at the Marriott Raleigh Durham Research Triangle Park. Enjoy the friendly and accommodating staff, highlighted by Cassandra and Mr. Mark, who go above and beyond to ensure a comfortable stay. The hotel features spacious rooms with comfortable beds, good TV, and responsive AC systems, perfect for a restful night. Indulge in delicious meals at the restaurant, offering a variety of options, and unwind at the well-appointed bar and seating areas. Ideal for both business and leisure travelers seeking comfort and convenience in Durham.

Homewood Suites by Hilton Raleigh-Durham Airport at RTP

Enjoy an exceptional stay at Homewood Suites by Hilton Raleigh-Durham Airport at RTP, where every detail is tailored to perfection. From the spacious and clean suites to the friendly and attentive staff, including Lynne, who ensures seamless experiences for large groups and individual guests alike. Despite ongoing construction, the hotel maintains its allure with convenient parking and a beautiful ambiance. Indulge in complimentary breakfast buffets and unwind in the welcoming reception area, making it a top choice for your stay in Durham.

DoubleTree by Hilton Raleigh Durham Airport at Research Triangle Park

Experience comfort and exceptional service at DoubleTree by Hilton Raleigh Durham Airport at Research Triangle Park. Enjoy quiet and cozy accommodations with great amenities like reliable AC, comfortable beds with thick pillows, and excellent hot water in the showers. The friendly and professional staff, including Charlie and Brandon, ensure a memorable stay with personalized service and delightful treats like their famous cookies. Whether you’re here for business or leisure, the well-kept hotel and inviting bar area with a diverse menu make it a standout choice in the RTP area.

Sheraton Imperial Hotel Raleigh-Durham Airport at Research Triangle Park

Conveniently located near the airport, Sheraton Imperial Hotel offers a superb stay with exceptional service from staff like Larissa in the cafe, known for her kindness and attention to dietary needs. Enjoy clean, comfortable rooms with plush beds and excellent dining options at the bar, equivalent to restaurant quality. The flawless check-in/out process and responsive maintenance, exemplified by Mark, ensure a memorable and satisfying visit.

WaterWalk Raleigh RTP

Experience a home away from home at WaterWalk Raleigh RTP, perfect for extended stays. Enjoy spacious, modern two-bedroom apartments with fully stocked kitchens, in-unit washer and dryer, and stylish decor. The staff ensures a comfortable stay with exceptional service. Conveniently located near essential amenities like a Super Walmart and eateries, the property offers ample parking and a safe environment. The quiet, peaceful atmosphere and top-notch facilities make it a highly recommended choice for travelers.

Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park

Experience the extraordinary Delta Hotels by Marriott Raleigh-Durham at Research Triangle Park. Immerse yourself in impeccably clean and spacious rooms, featuring innovative open-door showers. Enjoy convenient amenities like a complimentary shuttle and an elite pantry with delightful selections. Martice and the dedicated staff deliver exceptional service, ensuring every moment is memorable. Ideally located for business and leisure travelers, with seamless access to RTP and local attractions, this hotel guarantees a superior stay in Durham.

Sonesta Select Durham Research Triangle Park

Sonesta Select Durham Research Triangle Park offers a refreshing stay with its emphasis on cleanliness and comfort. The hospitable staff ensures a welcoming atmosphere, while amenities like a well-maintained coffee station and complimentary Starbucks add convenience. Although breakfast isn’t served, the nearby dining options and free laundry facilities enhance the value. Whether it’s the spacious rooms or the friendly service from Sanjay and the team, this hotel exceeds expectations, making it a great choice for your next visit.

SpringHill Suites Raleigh-Durham Airport/Research Triangle Park

SpringHill Suites Raleigh-Durham Airport/Research Triangle Park offers a welcoming stay with exceptional service from staff like Nicole at the front desk, who goes out of her way to ensure your comfort. The rooms are clean and comfortable, offering a pleasant retreat. Guests appreciate the complimentary breakfast and friendly service from both the desk and breakfast staff. Despite its location not being close to amenities, the hotel provides free parking and a convenient onsite store, making it a great choice for your stay in the area.

The Best Hotels in South Point

South Point in Durham, a modern enclave where sleek architecture meets southern hospitality, offers some of the best places to stay in Durham. Picture upscale boutiques and farm-to-table restaurants amidst manicured landscapes. It’s a neighborhood that blends contemporary comforts with a relaxed, welcoming atmosphere, ideal for exploring Durham in style.

Hilton Garden Inn Durham Southpoint

Enjoy a wonderful stay at Hilton Garden Inn Durham Southpoint, where exceptional service and a friendly atmosphere await you. The highlight is the outstanding breakfast service, with Natalie and Alicia providing attentive and cheerful hospitality that brightens your morning. Conveniently located near Southpoint Mall and popular dining options like Ruth’s Chris Steak House, PF Chang’s, and Chili’s, the hotel offers clean, comfortable rooms and a welcoming staff, making it a perfect choice for both short stops and extended stays.

Hyatt Place Durham Southpoint

Experience exceptional hospitality at Hyatt Place Durham Southpoint, where the staff, like L.A. at the front desk, ensure a welcoming and accommodating stay. Guests enjoy clean, comfortable rooms, with upgrades for loyal members. The spacious suites, ideal for groups, feature configurations with two queen beds and a sleeper sofa. Highlights include a diverse breakfast selection with gluten-free options, a great location near dining and shopping, and convenient charging stations for electric vehicles, making it a top choice for any traveler.

The Best Hotels in Brier Creek 

Brier Creek, where suburban tranquility meets culinary surprises, is home to some of the best areas to stay in Durham. Imagine upscale shopping and diverse dining options amid lush greenery. It’s a neighborhood that offers a peaceful retreat with easy access to the city’s vibrant offerings, perfect for unwinding in style.

Hyatt House Raleigh/Rdu/Brier Creek

Experience exceptional hospitality at Hyatt House Raleigh/RDU/Brier Creek. From the moment you arrive, the friendly front desk staff, including Lisa B., ensure a seamless stay. Enjoy clean, flawlessly maintained rooms and delicious dining options, highlighted by Sandra’s excellent bartending and service. Conveniently close to the airport with timely van service, this modern hotel offers a welcoming atmosphere and top-notch amenities, making it a standout choice for your visit to Durham.

Fairfield Inn & Suites Raleigh-Durham Airport/Brier Creek

Experience comfort and convenience at Fairfield Inn & Suites Raleigh-Durham Airport/Brier Creek, where friendly staff like Tyree and Ben ensure a seamless check-in and provide excellent local dining recommendations. Enjoy clean, spacious rooms, and a delicious breakfast selection. Conveniently located near RDU Airport with shuttle service, this hotel offers a pleasant stay with amenities like comfortable beds and a welcoming atmosphere, ideal for both short layovers and extended stays in the Raleigh-Durham area.

Aloft Raleigh Durham Airport Brier Creek’

Discover the vibrant energy of Aloft Raleigh-Durham Airport Brier Creek, where exceptional service meets a lively atmosphere. Enjoy top-notch amenities including a stylish bar with skilled bartenders, delicious food options, and spacious, well-kept rooms. Take advantage of the complimentary shuttle service covering the airport and nearby shops and restaurants, making your stay convenient and memorable. Whether relaxing in the WXYZ lounge or working out in the great gym facilities, this hotel promises a perfect blend of comfort and excitement for every guest.

Citysfied

For first-time visitors, the best places to stay in Durham include the vibrant city center, offering proximity to attractions like Durham Cathedral, as well as charming neighborhoods like Elvet and Gilesgate for a more local experience. With a range of accommodations from luxury hotels to cozy B&Bs, you’ll find the best places to stay in Durham to suit your needs and ensure a memorable visit.

XoXo,

Jona of backpackingwithabook.com